RORγt/DHODH-IN-3

SKU: orb1685894

Description

RORγt/DHODH-IN-3 ((S)-14d) is a potent, orally bioavailable dual inhibitor targeting RORγt and DHODH with IC50 values of 0.098 μM and 0.432 μM, respectively. It demonstrates significant anti-inflammatory activity in vivo, making it a valuable chemical probe for researching autoimmune diseases like psoriasis and multiple sclerosis in both cellular and animal models.

Research Area

Metabolism Research

Key Properties

• MW: 585.99
• Formula: C₂₄H₂₆ClF₆N₃O₃S
• Target: ROR,Others,Dehydrogenase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ROR,Others,Dehydrogenase