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RORγt agonist 1

SKU: orb1708653

Description

RORγt agonist 1 is a potent and orally bioavailable small molecule activator of the RORγt nuclear receptor, exhibiting an EC50 of 20.8 nM. It serves as a valuable research tool for investigating Th17 cell biology, autoimmune diseases, and cancer immunology in both cellular assays and animal models.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Images & Validation

Key Properties

CAS Number2377378-89-5
MW545.45
FormulaC24H17F6NO5S
SMILESS(=O)(=O)(N1C=2C(CC1CC(O)=O)=CC=C(C2)C3=CC(OC(F)F)=CC(F)=C3)C4=CC(C(F)(F)F)=CC=C4
TargetOthers,ROR

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Key Properties

No computed properties available.

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Protocol Information

RORγt agonist 1 (orb1708653)

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Available Sizes

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25 mg
$ 1,560.00
50 mg
$ 2,020.00
100 mg
$ 2,540.00
DispatchUsually dispatched within 6-8 weeks
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