RORγ antagonist 1

SKU: orb2277923

Description

RORγ antagonist 1 is a potent betulinic acid derivative functioning as a RORγ antagonist (K D = 0.18 µM). It exhibits anti-proliferative activity in pancreatic cancer models, suppressing RAS/MAPK and AKT/mTORC1 pathways while inducing caspase-dependent apoptosis in vitro and in vivo.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• MW: 540.86
• Formula: C₃₅H₆₀N₂O₂
• Target: ROR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

ROR