Roburic acid

SKU: orb1303613

Description

This small molecule compound acts as a dual inhibitor of both cyclooxygenase-1 (COX-1) and cyclooxygenase-2 (COX-2) enzymes. It is a useful research tool for investigating inflammatory pathways and related conditions in both in vitro and in vivo experimental models.

Research Area

Immunology & Inflammation, Neuroscience

Key Properties

• CAS Number: 6812-81-3
• MW: 440.70
• Purity: 99.98% (May vary between batches)
• Formula: C₃₀H₄₈O₂
• SMILES: C[C@@H]1CC[C@]2(C)CC[C@]3(C)C(=CC[C@@H]4[C@@](C)(CCC(O)=O)[C@@H](CC[C@@]34C)C(C)=C)[C@@H]2[C@H]1C
• Target: COX
• Solubility: DMSO:60.00 mg/mL (136.15 mM);10% DMSO+90% Corn Oil:2.50 mg/mL (5.67 mM)

Bioactivity

• Target IC50:
  COX-1:5 μM (IC50)|COX-2:9 μM (IC50)

Storage & Handling

• Storage: keep away from moisture,store under nitrogen | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

COX-2, COX-1, COX, Cyclooxygenase, inhibit, Inhibitor, Roburic acid

Compound Identifiers

PubChem CID

12315005