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RO8994

RO8994

Catalog Number: orb1304126

DispatchUsually dispatched within 3-5 working days
$ 140.00
Catalog Numberorb1304126
CategorySmall Molecules
DescriptionRO8994
CAS Number1309684-94-3
Purity98.87%
MW613.51
SMILESCOc1cc(ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21)C(N)=O
FormulaC31H31Cl2FN4O4
Biological ActivityRO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of 20 nM (MTT proliferation assays) and 5 nM (HTRF binding assays).
Storage-20°C
NoteFor research use only
Expiration Date12 months from date of receipt.
  • RO8994 [orb320152]

    [1309684-94-3]

    613.51

    C31H31Cl2FN4O4

    1 g, 100 mg, 250 mg