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Catalog Number | orb1304126 |
---|---|
Category | Small Molecules |
Description | RO8994 |
CAS Number | 1309684-94-3 |
Purity | 98.87% |
MW | 613.51 |
SMILES | COc1cc(ccc1NC(=O)[C@@H]1N[C@@H](CC(C)(C)C)[C@]2([C@H]1c1cccc(Cl)c1F)C(=O)Nc1cc(Cl)ccc21)C(N)=O |
Formula | C31H31Cl2FN4O4 |
Biological Activity | RO8994 is a highly effective and specific inhibitor of spiroindolinone small-molecule MDM2, with IC50 of 20 nM (MTT proliferation assays) and 5 nM (HTRF binding assays). |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |