Ro60-0175

SKU: orb1303569

Description

Ro60-0175 fumarate is a selective dual agonist for the 5-HT2B and 5-HT2C serotonin receptor subtypes. It is a research tool used in vitro and in vivo to study receptor function, neuropharmacology, and behaviors related to feeding and addiction.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 169675-08-5
• MW: 226.68
• Purity: 97.52%
• Formula: C₁₁H₁₂ClFN₂
• SMILES: C[C@H](N)Cn1ccc2cc(F)c(Cl)cc12
• Target: 5-HT Receptor
• Solubility: DMSO:120 mg/mL (529.38 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:4 mg/mL (17.65 mM)

Bioactivity

• In Vivo:
  Ghrelin administration increased operant responding for food reward and that this effect was attenuated by pre-administration of intraperitoneal or ventral tegmental area Ro60-0175.

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Ro60 0175, Ro600175, Ro-60-0175, Ro60-0175, yohimbine, selective, Serotonin Receptor, self-administration, inhibit, Inhibitor, 5-HT Receptor, 5-HT2C, 5HT Receptor, 5HTReceptor, 5-hydroxytryptamine Receptor, drug-seeking, contextual cues, cocaine

Compound Identifiers

PubChem CID

3045227