RO-3

SKU: orb1301731

Description

RO3 is a selective small molecule antagonist for homomeric P2X3 and heteromeric P2X2/3 receptors. It is a valuable research tool for investigating the role of these purinergic receptors in pain signaling, cough reflexes, and bladder function in both in vitro and in vivo studies.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1026582-88-6
• MW: 302.37
• Purity: 99.87% (May vary between batches)
• Formula: C₁₆H₂₂N₄O₂
• SMILES: COc1cc(Cc2cnc(N)nc2N)c(cc1OC)C(C)C
• Target: P2X Receptor
• Solubility: DMSO:3.03 mg/mL (10.02 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:1 mg/mL (3.31 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

CNS penetration, Inhibitor, pain, lower urinary tract dysfunction, inhibit, oral, P2X3, P2X Receptor, P2XReceptor, P2XRs, RO 3, RO3, RO-3

Compound Identifiers

PubChem CID

11289644