Ro 16-6028

SKU: orb1473105

Description

Bretazenil, also known as Ro 16-6028, is GABA A receptor agonist potentially for the treatment of anxiety disorders. Bretazenil differs from traditional 1,4-benzodiazepines by being a partial agonist and because it binds to α1, α2, α3, α4, α5 and α6 subunit containing GABAA receptor benzodiazepine receptor complexes. 1,4-benzodiazepines bind only to α1, α2, α3 and α5 GABAA benzodiazepine receptor complexes.

Key Properties

• CAS Number: 84379-13-5
• MW: 418.2844
• Purity: >98%
• Formula: C₁₉H₂₀N₃O₃BR
• SMILES: CC(C)(C)OC(=O)C1=C2[C@@H]3CCCN3C(=O)C4=C(C=CC=C4N2C=N1)Br

Storage & Handling

• Disclaimer: For research use only