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RNA polymerase II-IN-2

SKU: orb1982771

Description

RNA polymerase II-IN-2 (compound 20iii) is a potent Pol II inhibitor with a Ki of 9.5 nM. It exhibits significant cytotoxicity, being 2- and 5-fold more toxic than α-amanitin in CHO and HEK293 cells, respectively. This inhibitor is a valuable tool for studying transcription mechanisms and cancer cell biology in vitro.

Research Area

Cell Biology, Molecular Biology

Images & Validation

Key Properties

MW915.02
FormulaC41H58N10O12S
TargetOthers

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information