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RMC-6236

SKU: orb2900534

Description

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.

Images & Validation

Key Properties

CAS Number2765081-21-6
MW811.05
Purity>98% (HPLC)
FormulaC44H58N8O5S
SMILESO=C1OCC(C)(C)CC=2C3=CC(=CC=C3N(C2C=4C=C(C=NC4C(OC)C)N5CCN(C)CC5)CC)C=6N=C(SC6)CC(NC(=O)C7CC7C)C(=O)N8NC1CCC8
TargetRas
SolubilityIn Vitro: DMSO : 250 mg/mL (308.24 mM; Ultrasonic )

Bioactivity

In Vitro
RAS-IN-2 (Compound A122) (5 days) inhibits cell viability with an IC50 of 1-10 μM against AsPC-1 (K-Ras G12D).

Storage & Handling

StorageStorage temperature: -20°C. Stability: ≥ 2 years
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information