RMC-4630

SKU: orb1303503

Description

RMC-4630 (SHP2-IN-7) is a potent and selective allosteric inhibitor of the SHP2 phosphatase. It is a valuable research tool for investigating oncogenic signaling pathways in vitro and has demonstrated antitumor activity in preclinical in vivo models for cancer research.

Research Area

Metabolism Research

Key Properties

• CAS Number: 2172652-48-9
• MW: 450.99
• Purity: 99.89% (May vary between batches)
• Formula: C₂₀H₂₇ClN₆O₂S
• SMILES: C[C@@H]1OCC2(CCN(CC2)c2nc(C)c(Sc3ccnc(N)c3Cl)nc2CO)[C@@H]1N
• Target: Phosphatase
• Solubility: DMSO:45 mg/mL (99.78 mM);10% DMSO+40% PEG300+5% Tween-80+45% Saline:2 mg/mL (4.43 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Inhibitor, inhibit, SHP2-IN-7, SHP-2, Phosphatase, RMC 4630, RMC4630, RMC-4630

Compound Identifiers

PubChem CID

134182831