RKS-262

SKU: orb1737931

Description

RKS262 is a cyclin/CDK inhibitor derived from Nifurtimox, which is in phase II trials for neuroblastoma. It shows potent in vitro cytotoxicity in NCI(60) assays, with high sensitivity in leukemia cells (GI50 ~10 nM) and resistance in some NSCLC lines (GI50 >1 µM).

Key Properties

• CAS Number: 1041469-97-9
• MW: 433.7
• Formula: C₁₅H₁₄BrClN₂O₄S
• SMILES: ClC=1C=2C(OC(=O)C1C=NN3C(C)CS(=O)(=O)CC3)=CC=C(Br)C2
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

59405763