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RKI1313

SKU: orb1306750

Description

RKI1313 is a selective ROCK inhibitor that blocks ROCK-dependent signaling, leading to inhibition of cytoskeletal reorganization, colony formation, migration, and invasion. It is a valuable research tool for studying Rho/ROCK pathways in cancer cell biology, fibrosis, and neurological disorders in both in vitro and in vivo models.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Images & Validation

Key Properties

CAS Number1342276-76-9
MW340.4
Purity99.70% (May vary between batches)
FormulaC17H16N4O2S
SMILESN(C(NCC1=CC(OC)=CC=C1)=O)C2=NC(=CS2)C=3C=CN=CC3
TargetROCK
SolubilityDMSO:55 mg/mL (161.57 mM)

Bioactivity

Target IC50
ROCK2:8 μM|ROCK1:34 μM

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

Alternative Names

anticancer, migration, inhibit, Inhibitor, Rho-kinase, Rho-associated kinase, RKI 1313, RKI1313, RKI-1313, ROK, ROCK, ROCK2, ROCK1, ROCK substrates, Rho-associated protein kinase

Similar Products

  • RKI-1313 [orb1226506]

    >98% (HPLC)

    1342276-76-9

    340.4

    C17H16N4O2S

    2 mg, 5 mg, 10 mg, 25 mg, 50 mg, 100 mg, 200 mg, 500 mg, 1 g
Quality Guarantee

Quality Guarantee

Explore bioreagents carefree to elevate your research. All our products are rigorously tested for performance. If a product does not perform as described on its datasheet, our scientific support team will provide expert troubleshooting, a prompt replacement, or a refund. For full details, please see our Terms & Conditions and Buying Guide. Contact us at [email protected].

Key Properties

No computed properties available.

Protocol Information

Available Sizes

Select a size below

1 mg
$ 110.00
5 mg
$ 160.00
1 ml x 10 mM (in DMSO)
$ 170.00
10 mg
$ 220.00
25 mg
$ 350.00
50 mg
$ 500.00
100 mg
$ 690.00
DispatchUsually dispatched within 5-10 working days
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