RKI-1447 dihydrochloride

SKU: orb1688133

Description

RKI 1447 dihydrochloride is a potent and selective ROCK inhibitor with IC50 values of 14.5 nM for ROCK1 and 6.2 nM for ROCK2. It has been shown in research to suppress colorectal cancer cell proliferation and induce apoptosis in vitro, supporting its investigation in oncology and cell signaling studies.

Research Area

Cell Biology, Signal Transduction, Stem Cell & Developmental Biology

Key Properties

• CAS Number: 1782109-09-4
• MW: 399.29
• Formula: C₁₆H₁₆Cl₂N₄O₂S
• SMILES: Cl.Cl.Oc1cccc(CNC(=O)Nc2nc(cs2)-c2ccncc2)c1
• Target: Others

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

90489001