RK-20448

SKU: orb1737675

Description

RK-20448 is a cis-isomer of A-419259 and functions as a potent ATP-competitive inhibitor targeting Lck, Src, and VEGFR2/KDR, among other kinases like BLK and Fyn. This small molecule is a valuable research tool for studying T-cell signaling and angiogenesis in both cellular and biochemical assays.

Research Area

Cardiovascular Research, Signal Transduction

Key Properties

• CAS Number: 479501-40-1
• MW: 482.62
• Formula: C₂₉H₃₄N₆O
• SMILES: NC1=C2C(=CN(C2=NC=N1)[C@@H]3CC[C@@H](CC3)N4CCN(C)CC4)C5=CC=C(OC6=CC=CC=C6)C=C5
• Target: Src,Others,VEGFR,Tie-2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

6539952