Ritodrine hydrochloride

• Catalog Number: orb1308635
• Category: Small Molecules
• Description: Ritodrine hydrochloride
• CAS Number: 23239-51-2
• Purity: 99.89%
• MW: 323.82
• SMILES: Cl.C[C@H](NCCc1ccc(O)cc1)[C@H](O)c1ccc(O)cc1
• Formula: C₁₇H₂₁NO₃·HCl
• Biological Activity: Ritodrine hydrochloride (NSC 291565) binds to and activates beta-2 adrenergic receptors of myometrial cells in the uterus, which decreases the intensity and frequency of uterine contractions. Ritodrine hydrochloride (NSC 291565) is a phenethylamine derivative with tocolytic activity. Specifically, Ritodrine hydrochloride (NSC 291565) probably activates adenyl cyclase, thereby increasing production of cyclic adenosine monophosphate (cAMP), which in turn enhances the efflux of calcium from vascular smooth muscle cells. A lack of intracellular calcium prevents uterine myometrial contractions. In addition, this agent may directly inactivate myosin light chain kinase, a critical enzyme necessary for the initiation of muscle contractions.
• Note: For research use only
• Expiration Date: 12 months from date of receipt.