RIPK3-IN-1

SKU: orb1686497

Description

RIPK3-IN-1

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2361139-70-8
• MW: 512.53
• Purity: 98.27% (May vary between batches)
• Formula: C₂₉H₂₅FN₄O₄
• SMILES: Cc1c(C)c(Oc2ccnc(NC(=O)C3CC3)c2)ccc1NC(=O)c1cccn(-c2ccc(F)cc2)c1=O
• Target: Apoptosis,c-Met/HGFR,RIP kinase

Bioactivity

• Target IC50:
  B-Raf:0.15 μM|SRC:0.075 μM|MAP4K3:0.012 μM|ABL:0.37 μM|RIPK3:9.1 nM
• In Vitro:
  RIPK3-IN-1 inhibits ABL, BRAF/V599E, MAP4K3, and SRC with IC50 values of 0.37, 0.15, 0.012, and 0.075 μM, respectively.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

cMet/HGFR, c-Met, cMet, Apoptosis, HGFR, RIP kinase, RIPK1, RIPK2, RIPkinase

Compound Identifiers

PubChem CID

138393291