RIPK2-IN-6

SKU: orb2802148

Description

RIPK2-IN-6 (Compound 15a) is a selective RIPK2 inhibitor that blocks its phosphorylation, leading to the inhibition of downstream NF-κB and MAPK signaling. This compound has shown anti-inflammatory and anti-fibrotic efficacy in a DSS-induced colitis mouse model, supporting its use in researching inflammatory and fibrotic diseases.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2242432-02-4
• MW: 395.45
• Formula: C₂₆H₂₁NO₃
• SMILES: O=C1C2=C(OC=C2C)C3=CC=C4C=5C3=C1N(C5C(=O)CC4(C)C)CC=6C=CC=CC6
• Target: RIP kinase,p38 MAPK,NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

171347543