RIPK2 IN 10W

SKU: orb2893621

Description

RIPK2 IN 10W is a potent and highly selective RIPK2 inhibitor (IC50 = 0.6 nM), demonstrating >50,000-fold selectivity over RIPK1. It effectively blocks NOD2 signaling and MDP-induced cytokine production in vitro, supporting its research application in models of inflammatory diseases like inflammatory bowel disease.

Research Area

Cell Biology, Signal Transduction

Key Properties

• CAS Number: 2789711-40-4
• MW: 339.41
• Formula: C₁₉H₂₂FN₅
• SMILES: NC1=C2C(=CN(C2=NC=N1)[C@H]3CC[C@@H](N)CC3)C4=C(F)C=C(C)C=C4
• Target: RIP kinase

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

164946835