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RIPK1-IN-40

SKU: orb3211080

Description

RIPK1-IN-40 (Compound 51) is an inhibitor of RIPK1 and an anti-necroptotic agent, exhibiting an EC50 of 0.07 μM for necroptosis inhibition. It binds to the RIPK1 kinase domain, forming a hydrogen bond with Met95 and additional polar interactions with Asp156 to stabilize the binding, thereby inhibiting necroptosis. RIPK1-IN-40 is suitable for research in colorectal cancer.

Images & Validation

Key Properties

TargetRIP kinase,Necroptosis

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only
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Protocol Information