RIP2 Kinase Inhibitor 3

SKU: orb1708671

Description

RIP2 Kinase Inhibitor 3 is a highly potent and selective small molecule targeting RIP2 kinase, exhibiting an IC50 of 1 nM. It serves as a valuable research tool for investigating the role of RIP2 in NOD1/2 signaling pathways, applicable in both cellular and in vivo models of inflammatory and autoimmune diseases.

Research Area

Cell Biology, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 1398053-50-3
• MW: 388.48
• Purity: 99.52% (May vary between batches)
• Formula: C₁₉H₂₄N₄O₃S
• SMILES: COc1cc2nccc(Nc3n[nH]c(C)c3C)c2cc1S(=O)(=O)C(C)(C)C
• Target: RIP kinase
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.15 mM);DMSO:70 mg/mL (180.19 mM)

Bioactivity

• Target IC50:
  RIP2:1 nM

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

RIPkinase, RIP2, RIP2 Kinase Inhibitor 3, RIP-2 Kinase Inhibitor 3, RIP kinase

Compound Identifiers

PubChem CID

60194465