Rimegepant hemisulfate

SKU: orb3174414

Description

Rimegepant (BMS-927711) hemisulfate is a potent, orally active selective competitive antagonist of the calcitonin gene-related peptide (CGRP) receptor, with a Ki of 0.027 nM and an IC50 of 0.14 nM for the hCGRP receptor. Rimegepant hemisulfate is utilized in migraine research.

Research Area

Neuroscience, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1642783-82-1
• MW: 583.605
• Formula: C₂₈H₂₈F₂N₆O₃.1/2H₂O₄S
• SMILES: O=S(O)(O)=O.O=C1N(C2CCN(CC2)C(O[C@H]3C4=NC=CC=C4[C@H]([C@H](C5=C(C(F)=CC=C5)F)CC3)N)=O)C6=CC=CN=C6N1.O=C7N(C8CCN(CC8)C(O[C@H]9C%10=NC=CC=C%10[C@H]([C@H](C%11=C(C(F)=CC=C%11)F)CC9)N)=O)C%12=CC=CN=C%12N7
• Target: CGRP Receptor

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

CGRP Receptor