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Catalog Number | orb1707087 |
---|---|
Category | Small Molecules |
Description | Ribociclib hydrochloride |
CAS Number | 1211443-80-9 |
Purity | 98.00% |
MW | 471 |
SMILES | Cl.CN(C)C(=O)c1cc2cnc(Nc3ccc(cn3)N3CCNCC3)nc2n1C1CCCC1 |
Formula | C23H31ClN8O |
Biological Activity | Ribociclib hydrochloride is a highly specific CDK4/6 inhibitor (IC50: 10 nM and 39 nM, respectively). It is over 1,000-fold less potent against the cyclin B/CDK1 complex. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |