Rhynchophylline

SKU: orb1300242

Description

Rhynchophylline is a neuroprotective alkaloid that acts as a non-competitive NMDA receptor antagonist. It has demonstrated protective effects against ischemic damage and glutamate-induced neuronal death in vitro, potentially via modulation of the Akt/mTOR pathway, and is used in neuroscience research.

Research Area

Metabolism Research, Pharmacology & Drug Discovery, Signal Transduction

Key Properties

• CAS Number: 76-66-4
• MW: 384.47
• Purity: 99.98% (May vary between batches)
• Formula: C₂₂H₂₈N₂O₄
• SMILES: CCC1CN2CCC3(C2CC1C(=COC)C(=O)OC)C(=O)Nc1ccccc31
• Target: NF-κB,Calcium Channel
• Solubility: 10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (5.2 mM);DMSO:28.06 mg/mL (72.98 mM)

Storage & Handling

• Storage: keep away from moisture,store at low temperature | Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Calcium Channel, CalciumChannel, inhibit, Mitrinermin, Mitrinermine, NF-κB, NFkB, NF-kB, NFκB, Nuclear factor-κB, Nuclear factor-kappaB, Inhibitor, Rhynchophyllin, Rhynchophylline, Rhyncophylline

Compound Identifiers

PubChem CID

409518