RH01386

SKU: orb1707844

Description

RH01386

Research Area

Cell Biology

Key Properties

• CAS Number: 301177-36-6
• MW: 424.4
• Purity: 99.82% (May vary between batches)
• Formula: C₁₈H₁₅F₃N₄O₃S
• SMILES: C(#N)C1=C(NC(SC2=C(N(=O)=O)C=C(C(F)(F)F)C=C2)=NC1=O)C3CCCCC3
• Target: Apoptosis,Others
• Solubility: DMSO:55 mg/mL (129.59 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (4.71 mM)

Bioactivity

• In Vitro:
  ATP levels in βTC6 cells treated with (tunicamycin) Tm increase by RH01386.RH01386 exhibits a EC50 value of 1.894 μM. RH01386 dose-dependently inhibits (tunicamycin) Tm-induced cell death, and inhibits the activity of caspase-3, a downstream effector of the apoptotic pathway in βTC6 cells.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

inhibit, Inhibitor, ER stress-induced β cell dysfunction, Apoptosis, RH01386, RH-01386, RH 01386, βTC6 cells, β cell, type 2 diabetes

Compound Identifiers

PubChem CID

135441816