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Catalog Number | orb1296422 |
---|---|
Category | Small Molecules |
Description | RFRP-1 (human) acetate(311309-25-8 free base) |
Purity | 96.84% |
MW | 1488.77 |
SMILES | NC([C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC([C@H]2N(CCC2)C([C@H](CC(C)C)NC([C@H](CC(N)=O)NC([C@H](C)NC([C@@H](NC([C@H](CO)NC([C@H](CC3=CN=CN3)NC([C@H]4N(CCC4)C([C@@H](N)CCSC)=O)=O)=O)=O)CC5=CC=CC=C5)=O)=O)=O)=O)=O)=O)=O)=O.CC(O)=O |
Formula | C69H105N19O16S |
Biological Activity | RFRP-1 (human) acetate is a potent endogenous NPFF receptor agonist (EC50 values are 0.0011 and 29 nM for NPFF2 and NPFF1, respectively). Attenuates contractile function of isolated rat and rabbit cardiac myocytes. Reduces heart rate, stroke volume, ejection fraction and cardiac output, and increases plasma prolactin levels in rats. GnIH homolog. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |