Rezivertinib hydrochloride

SKU: orb3210164

Description

Rezivertinib (BPI-7711) hydrochloride is an orally active, highly selective, and irreversible third-generation EGFR tyrosine kinase inhibitor (TKI). It demonstrates potent efficacy against common activating EGFR mutations and the resistant T790M mutation. Rezivertinib hydrochloride efficiently penetrates the central nervous system (CNS) and exhibits antitumor activity in conditions such as non-small cell lung cancer (NSCLC).

Key Properties

• CAS Number: 2170255-78-2
• MW: 523.03
• Formula: C₂₇H₃₁ClN₆O₃
• SMILES: Cl.O=C(C=C)NC1=CC(NC=2N=CC=C(N2)C3=CN(C=4C=CC=CC34)C)=C(OC)C=C1OCCN(C)C
• Target: EGFR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

EGFR