Retinyl palmitate

SKU: orb1309911

Description

Retinyl palmitate, a stable ester form of vitamin A, is a naturally occurring compound investigated for its potential chemopreventive and anticancer properties. Research applications include in vitro studies on cell differentiation and proliferation, as well as in vivo models exploring its role in cancer prevention and dermatology.

Research Area

Metabolism Research

Key Properties

• CAS Number: 79-81-2
• MW: 524.86
• Purity: 70.00% (May vary between batches)
• Formula: C₃₆H₆₀O₂
• SMILES: CCCCCCCCCCCCCCCC(=O)OC\C=C(/C)\C=C\C=C(/C)\C=C\C1=C(C)CCCC1(C)C
• Target: Endogenous Metabolite
• Solubility: DMSO:50 mg/mL (95.26 mM)

Bioactivity

• In Vivo:
  Vitamin A Palmitate (80 mg/kg daily p.o.) or (800 mg/kg once a week p.o.) dose-dependently decreases the size of papillomas in mice, the daily administration induces a somewhat higher extent of regression than the weekly application if the total doses are compared. Water miscible solutions of Vitamin A Palmitate as well as of Vitamin A acid given by the oral route elicit the same effect on papillomas. Vitamin A Palmitate (A single simultaneous injection of 150 g) enhances cell-mediated immunity to sheep red blood cells(SRBC) as early as 3 days following immunization, and the enhancement persists for at least 3 weeks.
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• In Vitro:
  The microencapsulation of vitamin A palmitate by gelatin-acacia complex is a promising method for converting an oily vitamin to solid powders for an aid to handling and ease of incorporation in preparations.
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Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Retinyl, Retinyl (Vitamin A) Palmitate, Retinol, Retinol palmitate, Retinyl palmitate, Vitamin A, Vitamin A palmitate, inhibit, EndogenousMetabolite, Inhibitor, Endogenous Metabolite

Compound Identifiers

PubChem CID

5280531