RET-IN-20

SKU: orb1744277

Description

RET-IN-20 is a potent small molecule RET inhibitor with an IC50 of 13.7 nM. It suppresses p-Ret and p-Shc signaling, leading to inhibited proliferation, induced apoptosis, and demonstrated anti-tumor activity in relevant research models for oncology studies.

Research Area

Cell Biology, Signal Transduction

Key Properties

• MW: 584.64
• Formula: C₃₂H₃₃FN₆O₄
• SMILES: CN1C=C(C(=N1)NC2=CC(=C(C=C2)OC3=C4C=C(C(=CC4=NC=C3)OC)C(=O)N)F)C(=O)NC56CC7CC(C5)CC(C7)C6
• Target: c-RET,Others,Apoptosis

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

166177029