RET-IN-19

SKU: orb1686199

Description

RET-IN-19 is a potent small molecule RET inhibitor effective against both wild-type (IC50: 6.8 nM) and V804M mutant (IC50: 13.51 nM) forms. It is a valuable research tool for investigating RET-driven cancers, including non-small cell lung cancer (NSCLC), in both cellular and animal model studies.

Research Area

Cardiovascular Research, Cell Biology, Epigenetics & Chromatin, Signal Transduction

Key Properties

• CAS Number: 2484919-71-1
• MW: 544.62
• Formula: C₂₈H₂₈N₆O₄S
• SMILES: N(C1=C2C(NC(=C2)C3=CC=C(S(C)(=O)=O)C=C3)=NC=N1)C4=CC=C(CC(NC=5C=C(C(C)(C)C)ON5)=O)C=C4
• Target: c-RET,Others,c-Fms,Aurora Kinase,EGFR,MAPK

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Compound Identifiers

PubChem CID

162672262