Resolvin D5 n-3 DPA

SKU: orb3174708

Description

Resolvin D5 n-3 DPA is a specific pro-resolving lipid mediator (SPM) derived from docosapentaenoic acid (DPA). It acts as an agonist for GPR101, GPR12, and GPR84 receptors, with EC50 values of 4.6 pM, 14 pM, and 1.5 pM, respectively. This compound exhibits potent pro-resolving and anti-inflammatory properties, reducing cell adhesion on TNF-α-activated human endothelial monolayers. It significantly enhances leukocyte-targeting activity by increasing the phagocytic capacity of neutrophils and macrophages to engulf bacteria. Resolvin D5 n-3 DPA is useful for studying intestinal inflammation.

Research Area

Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• CAS Number: 1609382-32-2
• MW: 362.51
• Formula: C₂₂H₃₄O₄
• SMILES: [C@@H](/C=C/C=C\C/C=C\C=C\[C@H](C/C=C\CC)O)(CCCCCC(O)=O)O
• Target: GPCR

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

GPCR