Reproxalap

SKU: orb1307807

Description

Reproxalap (NS-2) is a small molecule that covalently sequesters reactive aldehyde species like malondialdehyde and 4-hydroxynonenal. It is utilized in ophthalmic research, particularly for studying dry eye disease mechanisms, with applications in both in vitro assays and in vivo animal models.

Research Area

Cell Biology, Epigenetics & Chromatin, Protein Biochemistry, Signal Transduction

Key Properties

• CAS Number: 916056-79-6
• MW: 236.7
• Purity: 99.97% (May vary between batches)
• Formula: C₁₂H₁₃ClN₂O
• SMILES: CC(C)(O)c1nc2ccc(Cl)cc2cc1N
• Target: Caspase,Others,PKC
• Solubility: DMSO:55 mg/mL (232.36 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (8.45 mM)

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

ADX-102, ADX102, ADX 102, NS2, NS-2, NS 2, inhibit, Inhibitor, Reproxalap

Compound Identifiers

PubChem CID

16088030