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Catalog Number | orb1303198 |
---|---|
Category | Small Molecules |
Description | Repotrectinib |
CAS Number | [1802220-02-5] |
Purity | 99.92% |
MW | 355.37 |
SMILES | C[C@H]1CNC(=O)c2cnn3ccc(N[C@H](C)c4cc(F)ccc4O1)nc23 |
Formula | C18H18FN5O2 |
Biological Activity | Repotrectinib (TPX-0005) is a potent ALK/ROS1/TRK inhibitor, with IC50 of 1.01 nM, 5.3 nM, 1.08 nM and 1.26 nM for WT ALK, SRC, ALK L1196M and ALK G1202R, respectively. |
Storage | -20°C |
Note | For research use only |
Expiration Date | 12 months from date of receipt. |