Remdesivir de(ethylbutyl 2-aminopropanoate)

• Catalog Number: orb1982914
• Category: Small Molecules
• Description: Remdesivir de(ethylbutyl 2-aminopropanoate) is a recognized impurity in Remdesivir, a nucleoside analog demonstrating potent antiviral efficacy. It exhibits EC50 values of 74 nM against SARS-CoV and MERS-CoV in human airway epithelial (HAE) cells, and 30 nM against murine hepatitis virus in delayed brain tumor cells. Notably effective in vitro against SARS-CoV-2 (COVID-19) infection, Remdesivir has garnered attention for its application in controlling the spread of the virus, as supported by references [1] [2].
• Purity: 98.00%
• MW: 447.34
• Biological Activity: Remdesivir de(ethylbutyl 2-aminopropanoate) is a recognized impurity in Remdesivir, a nucleoside analog demonstrating potent antiviral efficacy. It exhibits EC50 values of 74 nM against SARS-CoV and MERS-CoV in human airway epithelial (HAE) cells, and 30 nM against murine hepatitis virus in delayed brain tumor cells. Notably effective in vitro against SARS-CoV-2 (COVID-19) infection, Remdesivir has garnered attention for its application in controlling the spread of the virus, as supported by references [1] [2].
• CAS Number: 2607871-93-0
• Formula: C₁₈H₁₈N₅O₇P
• SMILES: Nc1ncnn2c(ccc12)[C@@]1(O[C@H](COP(O)(=O)Oc2ccccc2)[C@@H](O)[C@H]1O)C#N
• Storage: -20°C
• Note: For research use only