(rel)-PROTAC ERRα Degrader-1

SKU: orb1987772

Description

(rel)-PROTAC ERRα Degrader-1 is a stereoisomer of PROTAC ERRα Degrader-1, a heterobifunctional degrader targeting estrogen-related receptor alpha (ERRα). This chimera employs an MDM2 ligand and an ERRα binder linked together, facilitating ubiquitin-mediated protein degradation for probing ERRα biology in cellular and biochemical assays.

Research Area

Cancer Biology, Metabolism Research, Pharmacology & Drug Discovery

Key Properties

• MW: 1108.91
• Formula: C₅₄H₄₉Cl₂F₆N₇O₈
• SMILES: O=C(N(CCN1CC(NCCNC(/C(C#N)=C/C2=CC(OC)=C(OCC(C=CC(C(F)(F)F)=C3)=C3C(F)(F)F)C=C2)=O)=O)CC1=O)N4[C@@H](C5=CC=C(Cl)C=C5)[C@@H](C6=CC=C(Cl)C=C6)N=C4C(C=CC(OC)=C7)=C7OC(C)C.[Relative Stereochemistry]
• Target: Estrogen Receptor/ERR,Others,PROTAC Linker

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

Estrogen Receptor/ERR,Others,PROTAC Linker