rel-Avibactam sodium

SKU: orb3174633

Description

rel-Avibactam (NXL-104) sodium is a β-lactamase inhibitor with broad-spectrum antibacterial activity. When combined with Ceftazidime, rel-Avibactam sodium exhibits significant inhibitory effects on Enterobacteriaceae producing Ambler class A and C β-lactamases. Its IC50 values are significantly lower than those of commonly used β-lactamase inhibitors like Clavulanic acid and Ticarcillin, demonstrating high efficacy against TEM-1 and P99 enzymes.

Key Properties

• CAS Number: 1383814-68-3
• MW: 289.24
• Formula: C₇H₁₂N₃NaO₆S
• SMILES: C(N)(=O)[C@@H]1[N@]2C(=O)N(OS(=O)(=O)O)[C@](C2)(CC1)[H].[Na]
• Target: Antibacterial

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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Gene Symbol

Antibacterial