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Regorafenib monohydrate
Catalog Number: orb1307433
| Catalog Number | orb1307433 |
|---|---|
| Category | Small Molecules |
| Description | Regorafenib monohydrate |
| CAS Number | 1019206-88-2 |
| Purity | 99.47% |
| MW | 500.83 |
| SMILES | O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1 |
| Formula | C21H17ClF4N4O4 |
| Biological Activity | Regorafenib Monohydrate is a novel oral multikinase inhibitor with IC50 values of 13, 4.2, 46, 22, 7, 1.5, 2.5, 28, 19 nM for VEGFR1, murine VEGFR2, murine VEGFR3, PDGFR-β, KIT, RET, RAF-1, B-RAF and B-RAF(V600E) respectively. |
| Note | For research use only |
| Expiration Date | 12 months from date of receipt. |
- Item 1 of 1
Regorafenib Monohydrate [orb322106]
≥99%
1019206-88-2
500.83
C21H15ClF4N4O3 H2O
100 mg, 25 mg, 5 mg, 1 mg Regorafenib monohydrate (BAY 73-4506) [orb385576]
[1019206-88-2]
500.83
C21H17ClF4N4O4
1 g, 100 mg, 250 mg, 10 mM * 1 mL in DMSO
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