Regorafenib monohydrate

SKU: orb1307433

Description

Research Area

Cardiovascular Research, Cell Biology, Signal Transduction

Images & Validation

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Key Properties

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CAS Number	1019206-88-2
MW	500.83
Purity	99.69%
Formula	C₂₁H₁₇ClF₄N₄O₄
SMILES	O.CNC(=O)c1cc(Oc2ccc(NC(=O)Nc3ccc(Cl)c(c3)C(F)(F)F)c(F)c2)ccn1
Target	Autophagy,PDGFR,FGFR,c-Kit,Tie-2,VEGFR,c-RET,Raf
Solubility	DMSO:20 mg/mL (39.93 mM);10% DMSO+40% PEG300+5% Tween 80+45% Saline:2 mg/mL (3.99 mM)

Storage & Handling

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Storage	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
Disclaimer	For research use only

Alternative Names

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RET, PDGFRβ, PDGFR, Regorafenib, Regorafenib monohydrate, Regorafenib Monohydrate, RAF-1, Raf kinases, Raf, tumor, VEGFR, Vascular endothelial growth factor receptor, Colo-205, cKit, cRET, BAY 73-4506, B-RAF, B-Raf (V600E), antiangiogenic, Antitumorigenic, Autophagy, 786-O, Inhibitor, HUVECs, Hep3B cell, HAoSMCs, inhibit, Kit, murine VEGFR2, murine VEGFR3, Platelet-derived growth factor receptor, NIH-3T3

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Gene Symbol

Autophagy,PDGFR,FGFR,c-Kit,Tie-2,VEGFR,c-RET,Raf

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