Recombinant Murine Interleukin-6

SKU: orb1906206

Description

Recombinant Murine Interleukin-6

Research Area

Immunology & Inflammation

Key Properties

• Source: Escherichia coli
• Expression System: Escherichia coli
• Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by the dose-dependent stimulation of the proliferation of IL-6-dependent murine 7TD1 cells is less than 0.02 ng/ml, corresponding to a specific activity of > 5 x107 IU/mg.
• Molecular Weight: Approximately 21.7 kDa, a single non-glycosylated polypeptide chain containing 188 amino acids.
• Protein Sequence: MFPTSQVRRG DFTEDTTPNR PVYTTSQVGG LITHVLWEIV EMRKELCNGN SDCMNNDDAL AENNLKLPEI QRNDGCYQTG YNQEICLLKI SSGLLEYHSY LEYMKNNLKD NKKDKARVLQ RDTETLIHIF NQEVKDLHKI VLPTPISNAL LTDKLESQKE WLRTKTIQFI LKSLEEFLKV TLRSTRQT
• Purity: > 97 % by SDS-PAGE and HPLC analyses.
• Endotoxins: Less than 1 EU/ug of rMuIL-6 as determined by LAL method.

Storage & Handling

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Form/Appearance: Lyophilized from a 0.2 μm filtered solution in 30 mM Acetic Acid, pH 3.0, 150 mM NaCl, 5 % Trehalose, 0.02 % Tween-20.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

B-cell hybridoma growth factor, Interleukin HP-1.

Quick Database Links

UniProt

P08505