Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor/TNFRSF12A

• Catalog Number: orb1906303
• Category: Proteins
• Description: Recombinant Human TNF-related Weak Inducer of Apoptosis Receptor/TNFRSF12A
• Form/Appearance: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Purity: > 95 % by SDS-PAGE and HPLC analyses.
• Protein Sequence: EQAPGTAPCS RGSSWSADLD KCMDCASCRA RPHSDFCLGC AAAPPAPFRL LWP
• UniProt ID: Q9NP84
• MW: Approximately 5.6 kDa, a single non-glycosylated polypeptide chain containing 53 amino acids.
• Expression System: Escherichia coli
• Endotoxins: Less than 1 EU/ug of rHuTWEAK Receptor as determined by LAL method.
• Source: Escherichia coli
• Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inhibiting TWEAK-dependent proliferation of human umbilical vein endothelial cells (HUVEC) is less than 30 ng/ml, corresponding to a specific activity of > 3.3 x104 IU/mg, in the presence of 15 ng/ml of rHuTWEAK.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Alternative names: TNFRSF12A, FGF-inducible 14, CD266
• Note: For research use only
• Expiration Date: 6 months from date of receipt.