Recombinant Human Interleukin-36 Receptor Antagonist Protein

• Catalog Number: orb1906318
• Category: Proteins
• Description: Recombinant Human Interleukin-36 Receptor Antagonist Protein
• Form/Appearance: Lyophilized from a 0.2 μm filtered concentrated solution in PBS, pH 7.4.
• Purity: > 95 % by SDS-PAGE and HPLC analyses.
• Protein Sequence: VLSGALCFRM KDSALKVLYL HNNQLLAGGL HAGKVIKGEE ISVVPNRWLD ASLSPVILGV QGGSQCLSCG VGQEPTLTLE PVNIMELYLG AKESKSFTFY RRDMGLTSSF ESAAYPGWFL CTVPEADQPV RLTQLPENGG WNAPITDFYF QQCD
• UniProt ID: Q9UBH0
• MW: Approximately 16.8 kDa, a single non-glycosylated polypeptide chain containing 154 amino acids.
• Expression System: Escherichia coli
• Endotoxins: Less than 1 EU/ug of rHuIL-36RA as determined by LAL method.
• Source: Escherichia coli
• Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by inhibiting IL-36 beta induced IL-8 secretion by human preadipocytes is less than 1.0 μg/ml, corresponding to a specific activity of > 1000 IU/mg in the presence of 20 ng/ml of recombinant human IL-36 beta.
• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Alternative names: IL-1RP3, IL-1HY1, IL-1 delta, IL-1F5, IL-1ra homol
• Note: For research use only