Human IL-17A&17F

• Catalog Number: orb2994531
• Category: Proteins
• Description: Recombinant Human Interleukin-17A/Interleukin-17F Heterodimer is produced by our Mammalian expression system and the target gene encoding Gly24-Ala155&Arg31-Gln163 is expressed with a 6His tag at the C-terminus.
• Conjugation: Unconjugated
• Tag: C-6His
• Form/Appearance: Lyophilized from a 0.2 μm filtered solution of 20mM PB, 150mM NaCl, 1mM EDTA, pH 7.4.
• Reconstitution: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Purity: SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.. SEC-HPLC: Greater than 95% as determined by SEC-HPLC.(QC verified)
• UniProt ID: Q16552
• MW: Predicted: 15.1&16 KDa. Observed: 15-25 KDa, reducing conditions
• Expression System: Human Cells
• Endotoxins: < 1 EU/µg as determined by LAL test.
• Biological Origin: Human
• Biological Activity: BLI: Loaded Biotinylated Human IL-17RA -His-Avi(Cat#orb2993686) on SA Biosensor, can bind Human IL-17A&17F-His(Cat#orb2994531) with an affinity constant of 8.6 pM as determined in BLI assay. Loaded Biotinylated Human IL-17RA-Fc(Cat#orb2993676) on Pro A Biosensor, can bind Human IL-17A&17F-His(Cat#orb2994531) with an affinity constant of 10.3 nM as determined in BLI assay.
• Expression Region: Gly24-Ala155&Arg31-Gln163
• Storage: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
• Alternative names: IL‑17A/F Heterodimer; IL-17A&IL-17F Heterodimer
• Note: For research use only