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Recombinant Human FGF2 Protein
Catalog Number: orb527074
| Catalog Number | orb527074 |
|---|---|
| Category | Proteins |
| Description | Fibroblast Growth Factor basic (FGF-basic/FGF-2) is a single-chain polypeptide growth factor that plays a significant role in the process of wound healing and is a potent inducer of angiogenesis. Several different forms of the human protein exist ranging from 18-24 kDa in size due to the use of alternative start sites within the fgf-2 gene. It has a 55 percent amino acid residue identity to FGF-1 and has potent heparin-binding activity. The growth factor is an extremely potent inducer of DNA synthesis in a variety of cell types from mesoderm and neuroectoderm lineages. It was originally named basic fibroblast growth factor based upon its chemical properties and to distinguish it from acidic fibroblast growth factor. Other homologous FGF belonging to the same family are int-2 (FGF-3), FGF-5, FGF-6, K-FGF and KGF (keratinocyte growth factor = FGF-7). All factors are products of different genes, some of which are Oncogene products (FGF-3, FGF-4, FGF-5). |
| Reactivity | Human |
| Form/Appearance | Lyophilized |
| Protein Sequence | PALPE DGGSG AFPPG HFKDP KRLYC KNGGF FLRIH PDGRV DGVRE KSDPH IKLQL QAEER GVVSI KGVCA NRYLA MKEDG RLLAS KCVTD ECFFF ERLES NNYNT YRSRK YTSWY VALKR TGQYK LGSKT GPGQK AILFL PMSAK S |
| UniProt ID | P09038 |
| MW | 16.5KD |
| Endotoxins | Less than 1 EU/μg of rHubFGF as determined by LAL method. |
| Source | E. Coli-derived P143-S288 |
| Storage | Lyophilized recombinant mouse Fibroblast Growth Factor basic (FGF-basic/FGF-2) remains stable up to 6 months at -80°C from date of receipt. Upon reconstitution, rhFGF2 remains stable up to 2 weeks at 4°C or up to 3 months at -20°C. |
| Note | For research use only |
- Item 1 of 2
Human FGF2 protein [orb605324]
Greater than 90% as determined by SDS-PAGE.
17.9 kDa
Yeast
100 μg, 1 mg, 20 μg - Item 1 of 1
- Item 1 of 1
Human FGFb (Q65I,C96S,N111G) Protein [orb1471749]
Greater than 95% as determined by reducing SDS-PAGE.
17.2 KDa
Mammalian
50 μg, 10 μg - Item 1 of 1
Human FGF2 Protein, Flag Tag [orb2321459]
The purity of the protein is greater than 85% as determined by SDS-PAGE and Coomassie blue staining.
The protein has a predicted molecular mass of 33.7 kDa after removal of the signal peptide.
Mammalian
10 μg, 50 μg, 100 μg - Item 1 of 1
Human FGF2 protein [orb604091]
Greater than 90% as determined by SDS-PAGE.
32.4 kDa
E.coli
20 μg, 100 μg, 1 mg
