Human BCMA

SKU: orb2994062

Description

Recombinant Human Tumor Necrosis Factor Receptor Superfamily Member 17 is produced by our Mammalian expression system and the target gene encoding Met1-Ala54 is expressed with a mouse IgG1 Fc tag at the C-terminus.

Key Properties

• Expression System: Human Cells
• Biological Origin: Human
• Biological Activity: BLI: Loaded Mouse APRIL-Fc(Cat#orb2994771) on AHC Biosensor, can bind Human BCMA-mFc(Cat#orb2994062) with an affinity constant of -3 nM as determined in BLI assay. Loaded Human BAFF-Fc(Cat#orb2994098) on AHC Biosensor, can bind Human BCMA-mFc(Cat#orb2994062) with an affinity constant of 0.15 nM as determined in BLI assay. Loaded Human APRIL-His(Cat#orb2994084) on HIS1K Biosensor, can bind Human BCMA-mFc(Cat#orb2994062) with an affinity constant of 0.36 nM as determined in BLI assay.
• Tag: C-mFc
• Molecular Weight: Predicted: 32.5 KDa. Observed: 35-42 KDa, reducing conditions
• Expression Region: Met1-Ala54
• Purity: SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxins: < 1 EU/µg as determined by LAL test.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
• Form/Appearance: Lyophilized from a 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Disclaimer: For research use only

Alternative Names

Tumor necrosis factor receptor superfamily member 17; B-cell maturation protein; CD269; Tnfrsf17; Bcm; Bcma

Quick Database Links

UniProt

Q02223