Recombinant Human B-Cell Maturation Antigen/TNFRSF17

SKU: orb1906305

Description

Recombinant Human B-Cell Maturation Antigen/TNFRSF17

Research Area

Immunology & Inflammation

Key Properties

• Source: Escherichia coli
• Expression System: Escherichia coli
• Biological Activity: Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit APRIL-mediated proliferation of anti-IgM stimulated murine B cells is no less than 40 ng/ml, corresponding to a specific activity of > 2.5 x104 IU/mg in the presence of 100 ng/ml human APRIL.
• Molecular Weight: Approximately 5.4 kDa, a single non-glycosylated polypeptide chain containing 50 amino acids.
• Protein Sequence: AGQCSQNEYF DSLLHACIPC QLRCSSNTPP LTCQRYCNAS VTNSVKGTNA
• Purity: > 98 % by SDS-PAGE and HPLC analyses.
• Endotoxins: Less than 1 EU/ug of rHuBCMA as determined by LAL method.

Storage & Handling

• Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.- 12 months from date of receipt, -20 to -70 °C as supplied.- 1 month, 2 to 8 °C under sterile conditions after reconstitution.- 3 months, -20 to -70 °C under sterile conditions after reconstitution.
• Form/Appearance: Lyophilized from a 0.2 μm filtered concentrated solution in 30 % acetonitrile, 0.1 % TFA.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

TNFRSF17, BCM, CD269

Quick Database Links

UniProt

Q02223