Recombinant Cynomolgus FcRN Protein

SKU: orb2994891

Description

Recombinant Cynomolgus Beta-2-microglobulin&IgG Receptor FcRn Large Subunit P51 is produced by our Mammalian expression system and the target gene encoding Ile21-Met119&Ala24-Ser297 is expressed with a Flag tag at the C-terminus, 6His tag at the C-terminus.

Key Properties

• Expression System: Human Cells
• Biological Origin: Cynomolgus
• Biological Activity: BLI: Loaded Recombinant Cynomolgus FcRn Heterodimer (C-6His) (Cat#orb2994891) on HIS1K Biosensor, can bind Anti-Human HER2 mAb(Cat#GMP-A062) with an affinity constant of 11.1 nM as determined in BLI assay. (Regularly tested)
• Tag: C-Flag-6His
• Molecular Weight: Predicted: 12.6&31.3 KDa. Observed: 14&33 KDa, reducing conditions
• Expression Region: Ile21-Met119&Ala24-Ser297
• Purity: SDS-PAGE: Greater than 95% as determined by reducing SDS-PAGE.
• Endotoxins: < 1 EU/µg as determined by LAL test.
• Conjugation: Unconjugated

Storage & Handling

• Storage: Lyophilized protein should be stored at ≤ -20°C, stable for one year after receipt. Reconstituted protein solution can be stored at 2-8°C for 2-7 days. Aliquots of reconstituted samples are stable at ≤ -20°C for 3 months.
• Form/Appearance: Lyophilized
• Buffer/Preservatives: 0.2 μm filtered solution of PBS, pH 7.4.
• Reconstitution: Always centrifuge tubes before opening.Do not mix by vortex or pipetting. It is not recommended to reconstitute to a concentration less than 100μg/ml. Dissolve the lyophilized protein in distilled water. Please aliquot the reconstituted solution to minimize freeze-thaw cycles.
• Expiration Date: 6 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

IgG receptor FcRn; Neonatal Fc receptor; FCRN

Quick Database Links

UniProt

Q8SPW0, Q8SPV9