Rebamipide

• Catalog Number: orb1308173
• Category: Small Molecules
• Description: Rebamipide
• CAS Number: 90098-04-7
• Purity: 99.90%
• MW: 370.79
• SMILES: OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C1=CC=C(Cl)C=C1
• Formula: C₁₉H₁₅ClN₂O₄
• Biological Activity: Rebamipide (OPC12759) is a quinolinone derivative with anti-ulcer and anti-inflammatory activities. Rebamipide induces cyclooxygenase 2 (COX2) synthesis which results in an increase in endogenous prostaglandin synthesis in the gastric mucosa. This agent also inhibits H. pylori-induced production of tumor necrosis factor (TNF) alpha and subsequent inflammation of the gastric mucosa. In addition, rebamipide scavenges oxygen-derived free radicals that potentially cause mucosal injury, and stimulates prostaglandin EP4 receptor gene expression followed by mucous secretion, thereby enhancing the gastric mucosal defense.
• Storage: -20°C
• Note: For research use only
• Expiration Date: 12 months from date of receipt.