Rebamipide

SKU: orb1308173

Description

Rebamipide is a quinolinone derivative that enhances gastric mucosal defense by inducing COX-2 and endogenous prostaglandin synthesis, scavenging free radicals, and inhibiting H. pylori-induced TNF-alpha. It is widely used in research on gastritis, ulcer models, and inflammation, with applications in both in vitro cellular studies and in vivo animal experiments.

Research Area

Pharmacology & Drug Discovery

Key Properties

• CAS Number: 90098-04-7
• MW: 370.79
• Purity: 99.90% (May vary between batches)
• Formula: C₁₉H₁₅ClN₂O₄
• SMILES: OC(=O)C(CC1=CC(=O)NC2=C1C=CC=C2)NC(=O)C1=CC=C(Cl)C=C1
• Target: Free radical scavengers,COX,Prostaglandin Receptor
• Solubility: DMSO:6.88 mg/mL (18.55 mM);Ethanol:< 1 mg/mL (insoluble or slightly soluble);H2O:< 1 mg/mL (insoluble or slightly soluble)

Storage & Handling

• Storage: Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

AGS cells, COX-2, Cyclooxygenase, COX, gastric cancer, gastritis, gastroduodenal ulcer, Free radical scavengers, Freeradicalscavengers, OPC 12759, OPC12759, OPC-12759, mucosal protection, inhibit, Inhibitor, Proamipide, ProstaglandinReceptor, Prostaglandin Receptor, Rebamipide, PGE2

Compound Identifiers

PubChem CID

5042