RDR03871

SKU: orb1304932

Description

RDR03871 is a small molecule inhibitor targeting MDM2, which functions by blocking the MDM2-p53 interaction to stabilize and activate the p53 tumor suppressor pathway. It is utilized in oncology research for studying p53-mediated responses in both cellular and animal models of cancer.

Research Area

Cell Biology

Key Properties

• CAS Number: 286008-51-3
• MW: 408.81
• Purity: 97.78% (May vary between batches)
• Formula: C₁₈H₁₆ClF₃N₆
• SMILES: N(CCNC=1N=C(C(F)(F)F)C=CC1)C2=NC(=NC(C)=C2Cl)C3=CC=CC=N3
• Target: MDM-2/p53,Mdm2
• Solubility: DMSO:4.09 mg/mL (10 mM)

Bioactivity

• In Vitro:
  RDR03871 dissociated the MDM2/p53 with IC50 of 12.9nM in quantitative sandwich immune-enzymatic assays.

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Alternative Names

Mdm2, ZINC 20458540, ZINC20458540, ZINC-20458540, RDR 03871, RDR03871, RDR-03871

Compound Identifiers

PubChem CID

2725962