RBM1-151

SKU: orb3136582

Description

RBM1-151 is a 1-deoxy derivative and vinyl analog of RBM14-C12, serving as a fluorescent substrate for amidases (Ex/Em = 355/460 nm). It is hydrolyzed by acidic ceramidase (AC) (appKm = 7.0 μM; appVmax = 99.3 nM/min), N-acylethanolamine hydrolyzing acid amidase (appKm = 0.73 μM; appVmax = 0.24 nM/min), and fatty acid amide hydrolase (FAAH) (appKm = 3.6 μM; appVmax = 7.6 nM/min), but is not hydrolyzed by other ceramidases. RBM1-151 is useful for studying the basic biology of lipid amidase functions and for potential diagnostic/prognostic assessments in disorders involving AC, NAAA, or FAAH dysregulation, such as Farber disease and cancer.

Key Properties

• Target: Others
• Molecular Weight: 471.63
• CAS Number: 3077081-47-8
• Formula: C₂₈H₄₁NO₅
• SMILES: O(C/C=C/C[C@H]([C@@H](NC(CCCCCCCCCCC)=O)C)O)C=1C=C2C(=CC1)C=CC(=O)O2

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

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