Ratutrelvir

SKU: orb3210700

Description

Ratutrelvir is an inhibitor of NF-κBp65. It impedes the translocation of NF-κBp65 from the cytoplasm to the nucleus, reduces the phosphorylation levels of NF-κBp65 and IκBα, and inhibits the DNA binding activity of NF-κBp65. Additionally, Ratutrelvir can suppress the migration and invasion capabilities of breast cancer cells, decrease their survival rates, and reduce their colony-forming ability. It is applicable for research in luminal A-type breast cancer.

Key Properties

• CAS Number: 2929236-94-0
• MW: 547.57
• Formula: C₂₇H₃₂F₃N₅O₄
• SMILES: C(N[C@@H](CC1C=2C(NC1=O)=CC=CC2)C#N)(=O)[C@@H]3[C@@]4([C@@](C4(C)C)(CN3C([C@@H](NC(C(F)(F)F)=O)C(C)(C)C)=O)[H])[H]
• Target: NF-κB

Storage & Handling

• Storage: -20°C
• Expiration Date: 12 months from date of receipt.
• Disclaimer: For research use only

Quick Database Links

Gene Symbol

NF-κB