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RAS-IN-5

SKU: orb3174455

Description

RAS-IN-5 (Example 2) is a RAS inhibitor that effectively restrains the interaction between RAF1 and active KRAS mutant proteins or HRAS WT proteins. It significantly reduces the viability of KRAS, NRAS, and EGFR mutant cells. RAS-IN-5 is applicable for research in colon cancer, liver cancer, and non-small cell lung cancer.

Research Area

Signal Transduction

Images & Validation

Key Properties

CAS Number3061844-70-7
MW1002.2
FormulaC57H72N5O9P
SMILESO=C1OCC(C)(C)CC=2C3=CC(=CC=C3N(C2C=4C=C(C=CC4C(OC)C)P(=O)(C)C)CC)C=5C=C(O)C=C(C5)CC(NC(=O)C(N(C(=O)C6OCCC6C=7C=CC=CC7)C)C(C)C)C(=O)N8NC1CCC8
TargetRas

Storage & Handling

Storage-20°C
Expiration Date12 months from date of receipt.
DisclaimerFor research use only

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Protocol Information